I think everyone knows that I adore the Wraeththu series by Storm Constantine. It is one of the best original works of this generation, in my not so humble opinion. It combines fantasy with post apocalyptic fiction and creates a whole new creature. Literally.
What comes after humanity has run its course. The Wraeththu. Storm Constantine has created a world both alien and familiar at the same time. Everything is turned on its head but many still want to keep it the same. The character are rich and complex and the world she creates is multi-layered as the one we know.
This series is a must read for anyone who loves fiction.